After finding suitable scaling genes, we use their total read numbers per sample normalize the mito mapped reads.
The normalization smoothes the differences between replicates, but preserves the overall trend.
Based on unfiltered log2fold changes, the general trend continues: over all, mito rRNA transcription presumably is dampened by the suppression of HPR4 transcription.
When filtering based on pvalue (<=0.05) and p-adjusted (<= 0.05) only decreases in rRNA fragment expression remain.